[14] Pegylated interferon alfa is a pregnancy category C medication. Standard interferon alfa-2b has also been shown to have abortifacient effects in experimental animals. Use of either product is ...

GSK is conducting trials of bepirovirsen with other therapeutics, with the aim of increasing functional cure rates, including a phase 2b trial in combination with pegylated interferon and a phase ...

Treatment with xalnesiran, a small interfering RNA molecule, plus an immunomodulator resulted in hepatitis B surface antigen loss among adults with chronic HBV infection, according to a study ...

Interferon (IFN) has been shown to have antiviral, antiproliferative, and immunomodulatory effects, all of which may be important in HBV therapy. Thus, IFN increases cytotoxic T-cell immune ...

So far, licensed treatments include extended-effect interferon, pegylated interferon (IFN), ribvirin (RBV), protease inhibitors such as boceprevir, telaprevir, simeprevir, and sofosbuvir and ...