Oligodendrocyte progenitor cells (OPCs) are the major source of newly formed myelinating cells in the CNS. Thus, we studied in vitro platelets - OPCs interactions. Consistent with these observations, ...

A preliminary experiment was conducted to determine the response of microglia to varying doses of LPS. Microglia were exposed to 1 ng/ml, 10 ng/ml and 100 ng/ml of TNFα for 24 hours. This ...

reduce apoptosis and increase survival of mature oligodendrocytes in vitro. The effects of activated microglia on OPC and oligodendrocyte viability are present even as microglia themselves undergo ...