reduce apoptosis and increase survival of mature oligodendrocytes in vitro. The effects of activated microglia on OPC and oligodendrocyte viability are present even as microglia themselves undergo ...

One-Person Company registration is a popular choice for entrepreneurs seeking limited liability and a separate legal entity. An OPC is a unique business structure that allows a single individual to ...

Oligodendrocyte progenitor cells (OPCs) are the major source of newly formed myelinating cells in the CNS. Thus, we studied in vitro platelets - OPCs interactions. Consistent with these observations, ...

A preliminary experiment was conducted to determine the response of microglia to varying doses of LPS. Microglia were exposed to 1 ng/ml, 10 ng/ml and 100 ng/ml of TNFα for 24 hours. This ...

1 Department of Cellular Neurophysiology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic (ASCR), Prague, Czechia 2 Second Faculty of Medicine, Charles University, Prague ...

2019). They demonstrated that, as opposed to the control group, animals treated with hP-MSCs and hP-MSC-EVs displayed increased “differentiation of endogenous oligodendrocyte precursor cells into ...

Periventricular leukomalacia (PVL), the major substrate of neurologic deficits in premature infants, is associated with reduced white matter volume. Using immunomarkers of axonal pathology [β ...

Recent studies have identified alterations in microglia leading to detrimental effects on the pruning process of both synapses, neural progenitor cells, and more recently, oligodendrocytes. Dr. Nemes ...