Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. Nature Genetics , 2024; 56 (12): 2659 DOI: 10.1038/s41588-024-01764 ...

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The NLRP3 inflammasome is a key inflammation driver linked to central nervous system (CNS) disorders, metabolic diseases, and aging-related conditions. JOTROL, Jupiter’s flagship product ...

A new study from Karolinska Institutet and Mayo Clinic has revealed important insights into brain degeneration in dementia with Lewy bodies (DLB). This research, published in JAMA Neurology ...

InflammX’s pipeline includes a cutting-edge, orally dosed, therapeutic candidate targeting a form of macular degeneration known as intermediate age-related macular ... inflammatory recycling innate ...

InflammX's pipeline includes a cutting-edge, orally dosed, therapeutic candidate targeting a form of macular degeneration known as intermediate age-related macular ... inflammatory recycling innate ...

Background: The nod-like receptor family pyrin domain-containing 3 (NLRP3) has been implicated in various skin diseases. However, its role in mediating 2, 4-dinitrofluorobenzene (DNFB)-induced chronic ...

The Brooklyn-based startup is specifically targeting people with macular degeneration. The degenerative eye disease affects roughly 13% of U.S. residents aged 40 and up, according to figures from ...

NF-κB regulates the transcription of key components of inflammasomes involved in pyroptosis, particularly the NLRP3 inflammasome. Recent studies also indicate that NF-κB modulates the activation of ...

The 39th Golden Disc Awards kicked off last night! On January 4, the Golden Disc Awards held the first night of its ceremony at Fukuoka’s PayPay Dome in Japan. Although the awards were ...