Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

Once there, these monocytes differentiate into macrophages to address tissue damage (as exemplified ... CCL2 is thought to be involved in both the proliferation and differentiation of ...

Uncontrolled hypertension is known to cause end organ damage, including heart failure, myocardial infarction, CKD and stroke (88). Circulating monocytes from hypertensive patients exhibit an increased ...

The authors present solid evidence for its increased expression in stimulated monocytes/macrophages, its direct bactericidal functions, as well as its role in the modulation of monocyte ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...

The aortas were excised, placed in 10% buffered formalin, and decalcified according to the standard protocol. The aortic samples were sectioned transversely at 5-mm intervals and stained with rabbit ...