Importantly, stress appears to imprint a “memory” on monocytes, altering their function even after the stress event. This phenomenon, linked to epigenetic changes, could explain the prolonged ...

Once there, these monocytes differentiate into macrophages to address tissue damage (as exemplified ... CCL2 is thought to be involved in both the proliferation and differentiation of ...

Uncontrolled hypertension is known to cause end organ damage, including heart failure, myocardial infarction, CKD and stroke (88). Circulating monocytes from hypertensive patients exhibit an increased ...

The authors present solid evidence for its increased expression in stimulated monocytes/macrophages, its direct bactericidal functions, as well as its role in the modulation of monocyte ...