PAD mRNA expression was evaluated by RT-PCR. Human PAD2 mRNA could be detected in equal amounts in monocytes and in macrophages (fig 2). No significant up or down regulation was observed during ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Macrophages from SLE patients overexpress ICAM-1 and this is reduced by corticosteroid treatment. Systemic Sclerosis (SSc) monocytes are reported to be more pro-fibrotic because they display increased ...

The authors present solid evidence for its increased expression in stimulated monocytes/macrophages, its direct bactericidal functions, as well as its role in the modulation of monocyte ...

The aim of this study was to test if adalimumab treatment could affect the influx of monocytes into the synovium. Methods A novel technique was used to analyse the migration of labelled autologous ...

This principle can be used to make monocytes magnetically steerable in order to improve tumor accumulation, e.g., for immunotherapy with chimeric antigen receptor (CAR) monocytes. Here, we ...

Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

It was recently shown that monocyte/macrophage infiltration into the liver upon injury is critically regulated by the CCL2/CCR2 axis and is functionally important for perpetuating hepatic inflammation ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...