Basecamp Research says it has augmented the AlphaFold2 artificial intelligence tool for predicting protein structures ... at modelling small-molecule interactions. The new model, called BaseFold ...

In the field of biopharmaceuticals, every technological innovation has the potential to revolutionize treatment strategies. Sanyou Bio's Intelligent Hundred-Trillion Molecule Library (AI-STAL) has ...

Ubiquitin is an intracellular signalling molecule that is conjugated to various ... the UBD and conformational changes following binding. Structures of ubiquitin–UBD complexes have revealed ...

Far from being uniform in structure and function ... Interferon-stimulated gene 15 (ISG15), a ubiquitin-like molecule with two ubiquitin fold repeats, contains the same C-terminal sequence ...

OpenAI just released o3-mini, a reasoning model that’s faster, cheaper, and more accurate than its predecessor. On Thursday, Microsoft announced that it’s rolling OpenAI's reasoning model o1 ...

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This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

A Hispanic girl is holding a molecular structure model. She points to something on the model. An African American girl points to something on the model with a pencil. A chalkboard is in the background ...

This article explores methods to enhance efficiency in the drug discovery and development pipeline, focusing on optimizing ...