A high-salt diet suppressed the growth of tumors in a mouse model of melanoma, apparently because of an interplay between the gut microbiome and natural killer cells.

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared ...

Researchers have revolutionized cancer immunotherapy by developing a way to grow T cells in the lab that live longer and ...

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...

Researchers identify glucose usage as one major divergence betweenT cells expanding in vitro versus those expanding in vivo.

The researchers used both in vivo and in vitro models to investigate the mechanisms underlying osteocyte death. They ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.