The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...

In line with that, our review highlights the well-accepted mechanisms of action and resistance to the therapy and discusses the progress that has been made toward successfully overcoming this ...

Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Key Laboratory of Mental Health of the Ministry of Education, Southern Medical ...

Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and vitamin K. Protein kinase R-like ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

There’s such an abundance that we can create a list purely of action shows to look forward to in 2025. Whether you’ve already finished season 2 of Squid Game and are hankering for more action ...

But sometimes you don’t want that! Sometimes you just want to escape the increasingly insane world out there into an action movie. Netflix has made a few of their own, but the bulk of the best ...

Because the immunoregulatory effects of A77 1726 occur at doses that inhibit DHODH but not tyrosine kinases, the interruption of de novo pyrimidine synthesis may be the primary mode of action. Recent ...

Defense mechanisms are rooted in Freud’s theory of personality.According to his model, the mind has three dueling forces: the id (unconscious and primitive urges for food, comfort, and sex), the ...

In recent years, Netflix has made serious investments in its action collection, and today, our list of the best action movies on Netflix is absolutely loaded with hit originals and blockbuster ...