The study was published in the journal JCI Insight. Macrophages are immune cells that reside in and protect the lungs and are also recruited to the lungs in high numbers during injury or disease ...

Macrophages are immune cells that reside in and protect the lungs and are also recruited to the lungs in high numbers during injury or disease. They are key to the initiation and resolution of ...

These macrophages were not present in the lung before infection (left) and most were no longer detected two weeks after infection (right). Blue spots are nuclei of normal lung cells.

DENVER — Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages ...

Stefan Ivanov, Lung Immunology & Pharmacology Groups ... to the accumulation of macrophages in the bronchoalveolar space. IL-17-producing CD4 cells, termed T helper (Th)-17 cells, are functionally ...

This macrophage population was predicted to be present in the lungs of animals that recovered from influenza infection and absent from the lungs of those that succumbed. Overall, we provide a ...

London, A team of Swedish researchers has revealed how different kinds of immune cells, called macrophages, develop in the lungs, and which of them may be behind severe lung diseases, a discovery ...

Our bodies have a defence against such invaders – cells called macrophages which can ‘eat up’ these particles and clear them out of our lungs again. The problem is keeping PM levels low ...

This Perspective discusses current knowledge of the diverse roles played by different macrophage populations within the Mycobacterium tuberculosis-infected lung. The underlying hypothesis is that ...

More information: Emily M. King et al, Gpnmb and Spp1 mark a conserved macrophage injury response masking fibrosis-specific programming in the lung, JCI Insight (2024). DOI: 10.1172/jci.insight.182700 ...