Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

The underlying regulatory mechanisms of metabolic switching are assessed by both in vitro and in vivo studies. Conclusions Selectively modulating the ‘context’ of glycolytic macrophages in HCC tumours ...

Methods Synovial tissues from normal patients and patients with OA were collected. M1 or M2-polarised macrophages in synovial tissues of patients with OA and OA mice were analysed by ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...

Faculty of Medical Technology, Prince of Songkla University, Songkhla 90110, Thailand Division of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand ...

Remarkably, TRAP staining indicated a pronounced increase in osteoclast formation within the ... Moreover, we delineated additional potential docking configurations and binding sites in Figure 6. The ...

Introduction: Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic ...

One of the best ways to rejuvenate a stale space is to upgrade any outdated cabinets with a new wood stain. Applying wood stain is an achievable do-it-yourself job, even if it's your first time. In ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Further, blockade of CCL2/CCR2 signalling markedly attenuated macrophage accumulation, synovitis and cartilage damage in mouse ... CML and HR performed immunofluorescent and H&E staining of synovium ...

These are pretreated and laundered industrial stain monitors that Andrea used during detergent testing. The bottom-middle monitor shows stains pretreated and washed with Tide Free & Gentle.