SON-1010, after receipt of data suggesting clinical benefit when administered as a monotherapy in patients with advanced solid tumors, enters combination evaluation with trabectedin (Yondelis®) with ...

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

Multiple TIGIT clinical data readouts anticipated throughout 2025, including >400 patients from two Phase 2 trials and one Phase 1/2 ...

An international team of UK and US scientists discovered that the activity of macrophages -- a type of white blood cell that engulf pathogens and cancer cells -- can be used to predict whether or not ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell ...

Early-onset head and neck squamous cell carcinoma (HNSCC) has been increasingly observed in recent years, exhibiting distinct tumor behavior and a unique tumor microenvironment (TME) compared to older ...

Panel A shows worldwide age-standardized incidence and mortality rates for cervical cancer in 2022. Data are from the GLOBOCAN database and were collated by the International Agency for Research ...

This was the site of an injury he sustained five months earlier while removing a patient's malignant abdominal tumor. The lump in the surgeon's hand measured 1.2 inches (3 centimeters) in diameter.