The cancer microenvironment, or tumour microenvironment, describes the non-cancerous cells present in the tumour. These include fibroblasts, immune cells and cells that comprise the blood vessels.

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Next to cancer cells, various cells of the immune tumor microenvironment (TME) express receptors of the ECS that critically determine tumor growth. The role of GPR55 in cancer cells has been widely ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

Early-onset head and neck squamous cell carcinoma (HNSCC) has been increasingly observed in recent years, exhibiting distinct tumor behavior and a unique tumor microenvironment (TME) compared to older ...

Finding ways to tackle tumour associated macrophages, part of the “tumour microenvironment” that ... This will involve moving its first cancer drug into clinical trials, and starting work ...

AI Innovation Unlocks Non-Surgical Way to Detect Brain Cancer Spread Jan. 14, 2025 — Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain ...

Multiple TIGIT clinical data readouts anticipated throughout 2025, including >400 patients from two Phase 2 trials and one Phase 1/2 ...

Further research into the different injury models at different time points showed that the microenvironment of the lung caused subtle changes in protein expression and macrophage survival.