Adipocytes and macrophages jointly express two FABPs ... of lipids to specific compartments in the cell, such as to the lipid droplet for storage; to the endoplasmic reticulum for signalling ...

Introduction: Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic ...

The central organelle within the hepatocyte that stores excess fat is the lipid droplet (LD). Scores of different proteins control the formation and use of LDs. A deficit in LD breakdown is believed ...

New findings from the VIB-UGent Center for Inflammation Research reveal that macrophage activation states are crucial for liver repair following injury. The study, led by Prof. Charlotte Scott and her ...

Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic inflammation ...

Aims Demonstration of lipid-laden macrophages in respiratory secretions has been suggested to be a marker of reflux and aspiration. However studies looking at the diagnostic value of quantifying ...

In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological ...

The lipid droplet complex is then phagocytosed by macrophages resulting in the foamy appearance on histology, and the formation of xanthomas clinically.1 2 4 The differential diagnoses include ...