Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic inflammation ...

Therefore, several PSC selective markers have been proposed to assess their purity and activity (figure 1). The most consistent marker of PSC quiescence is the presence of vitamin A droplets in the ...

No writing assistance was utilized in the production of this manuscript. Lipid metabolism in homozygous familial hypercholesterolemia (HoFH) is abnormal owing to lack of functional LDL receptors ...