Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more ...

Researchers at the Max Planck Institute of Biophysics and Heidelberg University have observed largely intact HIV-1 capsids as ...

Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Macrophages, key modulators of immune responses, play a dual role in both promoting and resolving inflammation. Exosomes, small extracellular vesicles released by various cells, carry bioactive ...

Perforin forms transmembrane pores in the plasma membrane, allowing granzymes to enter the target cell cytosol and trigger ...

Despite recent therapeutic breakthroughs, cancer patients continue to face high recurrence and mortality rates due to treatment resistance. Cancer stem cells (CSCs), a subpopulation with self-renewal ...

School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore ...

Those strongly affected included microglia and border-associated macrophages ... with human brains in terms of structure, function, genes, and cell types. "Aging is the most important risk ...

In a trailblazing advancement in cancer therapy, researchers at Korea Advanced Institute of Science and Technology (KAIST) have developed a technology that transforms colon cancer cells into ...