A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled “Nuclear lipid ...

研究利用果蝇作为衰老模型，发现了高表达于神经胶质细胞中的糖基转移酶Ugt35b对维持正常果蝇寿命至关重要。通过整合多组学数据（代谢组、转录组和蛋白组）发现神经胶质细胞中特异性表达Ugt35b在参与调节果蝇脑内甘油脂和甘油磷脂代谢，尤其是甘油三酯（triacylglycerol, TG）的水平。

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of ...

The quest to find solutions for Alzheimer's disease and other neurodegenerative disorders continues to be one of the most ...

该研究以“ The glial UDP-glycosyltransferase Ugt35b regulates longevity by maintaining lipid homeostasis in Drosophila （胶质细胞糖基转移酶 Ugt35b 通过维持脂质代谢稳态调控果蝇寿命）”为题发表在 Cell Reports 杂志上 脂滴（Lipid droplets, ...

Results showed trehalose suppressed the hypertrophy of fat cells in both types of mice and increased lipid droplets in the intestinal epithelium: these were excreted in the mice’s faeces.