"Driven by a keen interest in lipid droplet functions in aging and disease, we initiated this fruitful collaboration to harness cutting-edge SRS technology for studying lipid metabolism in ...

By integrating bulk nuclear RNA-seq from adipocyte nuclei of different sizes, we identify distinct adipocyte subpopulations categorized by size and functionality. These subpopulations follow two ...

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada Michael Smith Laboratories, University of British Columbia, Vancouver, ...

identifying unique subpopulations with distinct transcriptomic signatures (30). In AD, single-cell RNA sequencing has uncovered diverse microglial states, including disease-associated microglia (DAM), ...

The cargo of sEV is composed of lipids, proteins, nucleic acids, organelles and other elements. There are several markers that confirm the exosome’s structural organization, including CD63, CD81, CD9, ...

This study provides compelling evidence for functional subpopulations of β-cells responsible for Ca2+ signal initiation and maintenance using novel three-dimensional light sheet microscopy imaging and ...

Unsaturated fats are an essential part of your daily diet. Your body uses fats for energy, to keep cells working, produce hormones, and help your body absorb oil-based vitamins (A, D, E, and K). Since ...