Conclusion: The present work characterizes one of the earliest sequences in the establishment of pre-AC and suggests that subsets of EE-derived tubular membranes may serve as the earliest biomarkers ...

Globally, breast cancer represents the most common cancer and the primary cause of death by cancer in women. Lipids are crucial in human physiology, serving as vital energy reserves, structural ...

Biogenesis of membrane-bound organelles involves the synthesis, remodeling, and degradation of their constituent phospholipids. How these pathways regulate organelle size remains poorly understood.

In this study, we used temporal metabolomics on HeLa cells to show that MTCH2 deletion results in a high ATP demand, an oxidized cellular environment, and elevated utilization of lipids, amino acids, ...

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, ...

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, USA Department of Microbiology, UMass Chan Medical School, , USA ...

lipid droplet formation, and lipid lipolysis in the hypothalamus. These results fill in a missing but important gap in our understanding of brain region selective lipid metabolism in physiological ...

Bakovic, am an internationally recognized researcher in membrane biogenesis, nutrient transport ... was uniquely positioned to initiate the first studies on the regulation and function of this key ...