The goal of this review is to describe barrier function of the intestine, the structure of the tight junction, methods to evaluate intestinal permeability, and most importantly the relevance of ...

Data are accumulating that emphasize the important role of the intestinal barrier and intestinal permeability for health and disease. However, these terms are poorly defined, their assessment is a ...

The gut barrier encompasses several interactive, physical, and functional components, such as the gut microbiota, the mucus layer, the epithelial layer and the gut mucosal immunity. All these ...

Dysregulation of the gut microbiota can affect its metabolites and intestinal permeability, causing gut microbiota translocation, overactivation of the immune system, and exacerbation of the ...

We hypothesised that impaired intestinal barrier function is involved in the onset and persistence of ... In addition, abnormal expression of cell-to-cell adhesion proteins at the level of tight ...

College of Food Science and Engineering, Key Laboratory of Food Nutrition and Human Health in Universities of Shandong, Shandong Agricultural University, Taian 271018, China ...

Intestinal villi (singular: villus)are tiny, finger-like projections that line the interior (lumen) of the small intestine. The primary function of villi is to absorb nutrients from food and transfer ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

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Tight Junction Proteins: Proteins that help maintain the integrity of the intestinal barrier, preventing harmful substances from entering the bloodstream. This Nature Research Intelligence Topic ...