Epithelial cells that line the inner layer of the intestine tract supply a barrier for entrance of pathogenic microbes. In addition, epithelial cells actively contribute to pathogenesis of IBD by ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

To test how RANK–RANKL signalling directly affects intestinal epithelial cells, we exposed mouse and human intestinal organoids (self-organized 3D tissues derived from intestine-resident stem ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and ...

They found that the inner lining of the upper intestine, called the "epithelium" –composed of a variety of cells that are not ...

The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...

A contact protein printing technique enables researchers to control the formation of villi in human gut models, making it ...

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in PTPN2.

These cultures are derived from stem cells isolated from human intestinal tissue. The stem cells are propagated in vitro and form mature intestinal epithelium upon growth factor manipulation. In order ...