Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms. However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their ...

Scientists have officially grown a notochord—the tissues that act as the “GPS for the developing embryo” by guiding the ...

"These findings provide insight into the biology of the intervertebral disc," he ... by the lack of investigations on healthy human spinal discs. "Taken together, the currently known facts evoke ...

Therefore, automating the patient-specific modeling process is essential. Methods: We developed an automated and robust pipeline that generates and simulates biofidelic vertebrae and intervertebral ...

Francis Crick Institute scientists developed a rudimentary human spine via stem cells in a laboratory. They have created a “trunk-like structure” that is around 1 to 2 millimeters long. Despite its ...

(d) Forms an isotonic solution with human tissue and does not damage non-collagen protein substances ... This approach involved small-dose collagenase injection at an extradiscal target point of the ...

Christopher Shapley, DVM, CVA, CVCH, CVFT, talks about his multimodal approach for dogs with certain neurological diseases, and why it works ...

Jan. 16, 2025 — Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of ...

Syndesmophytes were scored in coronal and sagittal planes in eight quadrants per vertebral unit (VU) as absent=0, <50% of the intervertebral disc space (IDS)=1, ≥50%=2 or bridging the ... Results 49 ...