Background and aim: The importance of the hepatocyte ploidisation pattern to the control of cell proliferation and differentiation has been well established. However, there are no data that have ...

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You have full access to this article via your institution. Figure 2: Differential interaction of Apo2L trail versions with hepatocytes.

The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

A new milestone in nuclear physics has been achieved with the direct observation of three different deformations in the atomic nucleus of lead-190 (190 Pb). These deformations, associated with ...

The researchers have now come a step closer to mapping this island by discovering the shortest-lived superheavy nucleus known so far, which marks the position of the island's shoreline in nuclei ...

Spatial transcriptomics was combined with single-nucleus RNA sequencing to annotate healthy and fibrotic human livers, improving spatial resolution of hepatocytes and receptor-ligand interactions ...

bnHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Faculty of Medical Science, Medical University of Silesia, Katowice, Poland boSchool of Public Health, Tongji Medical ...

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Disorders of surfactant protein biology cause ...

The importance of the gastrointestinal microbiota (GM) in health and disease is widely recognized. Although less is known in fish than in mammals, advances in molecular techniques, such as 16S rRNA ...

Apolipoprotein C3 (apo C3) is primarily secreted by the liver and is involved in promoting sterile inflammation and organ damage under pathological conditions. Previous studies have shown that apo C3 ...