The results of a phase 2b ENLIVEN trial of FGF21 analogue pegozafermin showed it was able to reduce scarring (fibrosis) in the liver of NASH patients at more than three times the rate of a placebo ...
In experiments, if mice could not produce a gut protein, called Ffar4, the researchers found the gut colonies of B. vulgatus shrank. This, in turn, decreased the release of a hormone called FGF21, ...
The study indicated that increasing the population of Bacteroides vulgatus in diabetic mice contributed to the ... leading to decreased release of the hormone FGF21, which is associated with ...