such as endothelial cells and macrophages, exhibited higher senescence-related gene expression after PAGln treatment. In the lungs, fibroblasts also showed elevated markers of senescence.

A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) on December 12, 2024, Volume 16, Issue 22, titled “Arginase-II gene ...

Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. Senescence can be induced by unrepaired DNA damage ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight. Kamal is a freelance science journalist based in the UK with a PhD in virology ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

Our results suggest that increased Arg-II in non-skeletal muscle cells promotes age-associated sarcopenia, particularly in male mice."BUFFALO, NY ...