The successful and safe delivery of therapeutics relies on understanding how easily drugs can pass through biological ...

New research has outlined guidance for using AI to help bridge the gap between in silico, in vivo and in vitro drug testing.

Passive diffusion and transporters coexist to affect drug disposition. Join Research Fellow Li Di of Pfizer during this free interactive broadcast as she discusses why design principles that increase ...

Applications of the concept of drug-likeness, which involve consideration ... candidates owing to issues such as poor solubility and permeability. Seeking to understand why, Christopher Lipinski ...

Understanding how bacteria control the entry and efflux of chemicals helps us to explain and possibly reverse antimicrobial drug resistance. Even when antimicrobials gain access ... The combination of ...

Monash University researchers have revealed how the gut—and what we eat—regulates high blood pressure, opening the door to more specialized potential new drugs.

The gut and two cell regulators may pave the way to better high blood pressure drugs.Monash University researchers have revealed how the gut – and ...

The results establish that balancing solubility and permeability is essential for optimizing the efficacy of ...