In FCS, mutations in the lipoprotein lipase gene lead to an accumulation of chylomicrons in plasma resulting in severe hypertriglyceridemia.

Researchers from the University of Leicester, working with international collaborators, have unraveled a key mechanism by ...

As the year unfolds the biotech industry will look closely at these ten first-in-class drugs on track to reach FDA approval ...

It is almost exclusively caused by Wuchereria bancrofti in tropical areas. Chylomicrons and triglycerides are lost in the urine from an abnormal lymphourinary fistula due to obstructive lymphatic ...

In addition, cytoplasmic lipid droplets that greatly increased in size and number were strongly labelled by the SR-BI antibody whereas apolipoprotein A-1 positive chylomicrons were largely devoid of ...

2 Lipoprotein lipase is responsible for breaking down chylomicrons, large lipid-containing particles primarily composed of triglycerides. In FCS, impaired ability to break down chylomicrons leads ...

and enhanced clearance of TG from circulating TG-containing lipoproteins (VLDL and chylomicrons) from the bloodstream.

In FCS, mutations in the lipoprotein lipase gene lead to an accumulation of chylomicrons in plasma resulting in severe hypertriglyceridemia. Olezarsen, a ligand-conjugated antisense medication, ...

1 Department of Cardiology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China 2 Department of Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, ...

Absorbed fatty acids at gastrointestinal tract must be esterified into triglycerides (TGs), which can later be packaged into chylomicrons. The steric hindrance exerted by α-hydroxyl group on carbon 1 ...