These anionic chemical moieties are located within membrane proteoglycans (heparin sulfate proteoglycans: HSPGs; chondroitin sulfate proteoglycans: CSPGs; dermatan sulfate proteoglycans: DSPGs; ...
The central nervous system (CNS), composed of the brain, spinal cord, and retina, has a limited capacity to spontaneously regenerate and this, coupled with few regenerative strategies available ...
As the polysaccharides may have a similar structure it is not as apparent as it may be with other drug types, with the notable example of contamination of heparin with over-sulfated chondroitin ...