Each step was adjusted for multiple testing using Bonferroni correction. Results: Our analyses identified two proteins (Cathepsin B and ECHDC3) that met all the criteria to mediate the polygenic ...
Key Laboratory of Organosilicon Chemistry and Materials Technology of the Ministry of Education, Zhejiang Key Laboratory of Organosilicon Material Technology, College of Materials, Chemistry and ...
Pancreatic acini were coincubated in vitro from wild-type and cathepsin-B-deficient animals with phorbol-12-myristate-13-acetate (PMA)-activated neutrophils and macrophages, caerulein or TNFα, and ...
NLRP3 can be activated in response to extracellular ATP and K + efflux through the ATP-gated P2X7 channel, in response to cathepsin B release from damaged lysosomes or in response to reactive oxygen ...
AMP-activated protein kinase (AMPK), a key metabolic regulator, plays an essential role in the maintenance of energy balance in response to stress. Tuberculosis (TB), primarily caused by the pathogen ...
Lymph vessels and endothelial cells are associated with vessel tissues. Immune cells in the oesophagus include T cells, B cells, monocytes, macrophages, dendritic cells (DCs) and mast cells. The cell ...
Cluster B disorders are taxonomically grouped together by the DSM-V because a single, clear-cut diagnosis is very rare, and patients often exhibit a number of overlapping symptoms. For example ...
Hepatitis B (sometimes referred to as hep B) is a liver infection caused by the hepatitis B virus (HBV). It typically causes symptoms like stomach pain, dark urine, fatigue, fever, jaundice (yellowing ...