While COX-2 and its product, prostaglandin E2 (PGE2), are well-known for their involvement in inflammation and tumor growth, new research suggests that NSAIDs may also act through other pathways.
COX-2 levels increase during developmental synaptic remodeling 5 and upregulation of synaptic activity 6. Moreover, COX-2 is involved in the coupling of synaptic plasticity with cerebral blood flow 7.
This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...
Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...
Per ComicBook.com, Matt Murdock actor Charlie Cox revealed at this year’s FAN EXPO San Francisco that he already knows when he will start shooting new episodes of the forthcoming Disney+ series ...
Jeremy Strong Seems to Claps Back at Succession Costars Brian Cox and Kieran Culkin After Their Digs About His Acting Brian Cox Reveals Which of His Succession Kids He'd Be OK Spending Christmas ...
Consequently, levels of proinflammatory cytokines such as interleukins (IL-1, IL-6, IL-8) and tumor necrosis factor (TNF-α) increase, releasing catabolic factors such as nitric oxide (NO), matrix ...