This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Non-Asian GCs were significantly enriched in signatures related to T-cell biology, including CTLA-4 signalling. Similarly, in the TMA cohorts, non-Asian GCs showed significantly higher expression of T ...

Background: The nod-like receptor family pyrin domain-containing 3 (NLRP3) has been implicated in various skin diseases. However, its role in mediating 2, 4-dinitrofluorobenzene (DNFB)-induced chronic ...

Flow cytometry was used for the evaluation of surface markers or transgene expression. The following antibodies were used: anti-Mesothelin-APC (REA1057, Miltenyi Biotec), anti-CD3-APC (OKT3, BioLegend ...

Plates were coated overnight at 4°C with plate-bound anti-mouse CD3 antibody (2 μg/mL). Prior to plating ... Cells were then stained with zombie NIR (1:1000) and anti-CD16/32 (1:200) for 10 minutes ...

Bacterial outer membrane vesicles (OMVs) have emerged as promising vehicles for anticancer drug delivery due to their inherent tumor tropism, immune-stimulatory properties, and potential for ...

Objective Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory ...