This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...

4.2 Current status of CD19-CAR-T cell therapy for systemic sclerosis and autoimmune disease Existing research has preliminarily confirmed the feasibility and potential benefits of CD19 CAR-T cell ...

At the end of the incubation the cells were spun, supernatant aspirated, and the cells were stained with rat anti-mouse CD11b (Pacific blue), CD5 (PE), CD19 (APC), and incubated for 30 min on ice. The ...

Preclinical studies using transgenic mice expressing human CD19 have shown that pre-B cells and their malignant counterparts, as well as pre-existing antibody-producing and autoantibody-producing ...

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Institute for Advanced Optics, Hunan Institute of Science and Technology, Yueyang, Hunan 414006, China School of Information Science & Technology, Hunan Institute of Science and Technology, Yueyang, ...

A separate tube of the digested cell suspension was labeled for flow cytometry analysis of immune cells and stained with Zombie Violet (Biolegend Cat# 423114)as well as CD45-FITC [clone HI30] ...