B-cell depletion with unconjugated CD20 monoclonal antibody (mAb) is used to treat rheumatoid arthritis and other autoimmune diseases. CD20-targeted immunotherapy depletes mature B cells through ...

Although sustained remission free of disease-modifying antirheumatic drugs “does not seem attainable” for patients with ...

T-cell large granular lymphocytic (T-LGL) leukaemia is frequently associated with an autoimmune phenomenon; approximately one-third of patients have rheumatoid arthritis (RA). Intriguingly, one-third ...

Rheumatoid arthritis (RA) is a complex condition that is well characterised ... on the putative effects on the continuing inflammatory process of different synovial cell populations, including ...

constitute a promising experimental treatment for targeting autoreactive T cells in autoimmune diseases, including rheumatoid arthritis (RA). The authors' goal is to bring tolDC therapy for RA to the ...

Not only do free radicals damage cells, but they also have been linked to rheumatoid arthritis (RA) and inflammation. Green, leafy vegetables such as broccoli, spinach, Brussels sprouts, kale, Swiss ...

Women with an age at first birth (AFB) younger than 26 or older than 35 years have a higher risk for developing rheumatoid ...

for rheumatoid arthritis, methotrexate is responsible for hair loss in about 1% to 3% of people. The hair loss happens because methotrexate is doing what it’s supposed to do – stop cells from growing.

Objectives Programmed cell death protein 1 (PD-1)-expressing T cells are implicated in the pathogenesis of autoimmune inflammatory diseases such as rheumatoid arthritis. A subset of CXCR5 − T cells, ...

Tocilizumab biosimilar (CT-P47) is under development for the treatment of rheumatoid arthritis, giant cell arteritis (GCA), systemic juvenile idiopathic arthritis (sJIA), polyarticular juvenile ...