A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, ...

Bispecific antibodies combine two therapeutic antibodies into one, simultaneously utilizing the effect of both to benefit patients. However, currently available technologies to produce these two ...

causes cellular damage and alters thyroid gland function by humoral and cell-mediated mechanisms. Cellular damage occurs when sensitized T-lymphocytes and/or autoantibodies bind to thyroid cell ...

In part 2 of our interview with Katie Abouzahr, MD, Johnson & Johnson Innovative Medicine, we discuss the challenge inherent ...

Figure 1: Antibody design to improve homogeneity and ... In addition, many third-generation antibodies designed to trigger different mechanisms of action simultaneously (such as targeting growth ...

Mechanism of biotin interference with immunoassay methodologies. Immunoassays in this case report contain a solid phase with a wash step that physically separates the label-bound analyte/antibody ...