Ipsen and Sutro Biopharma entered a global licensing deal for STRO-003, an ADC targeting ROR1, overexpressed in cancers, ...

Sjögren’s antibody testing is done using a blood sample. It checks antibody levels, including anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). Anti-SS-A and anti-SS-B are ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Currently, apart from inactivated EV-A71 vaccines that were developed in China, no effective measures are available to prevent or treat NPEV infections. Antibody-mediated immunity is crucial for ...

We are excited to announce that makers can now visualize and manage existing tables in the ERD table designer, data workspace! Now, instead of starting from scratch, you can use your existing tables ...

MIT’s new AI model predicts antibody structures with greater accuracy, aiding disease treatment and streamlining drug discovery. With this model, researchers may be able to discover antibody drugs ...

Oxford, UK and San Jose, California, 9 January 2024 - Oxford BioTherapeutics (OBT), a clinical stage oncology company with a pipeline of immuno-oncology and Antibody Drug Conjugate (ADC)-based ...

The World Athletics scoring tables have been updated for 2025 and are available to download from the World Athletics website. These tables are separate from the combined events scoring system, which ...

Starting from the third day after the stroke, male mice were injected intraperitoneally with clozapine-N-oxide every day to activate excitatory neurons. C1q-blocking antibody and annexin V were used ...

Type 1 virus was recovered after 52 volunteer challenges, and a fourfold or greater rise in serum neutralizing or hemagglutination-inhibiting antibody was detected in 46 cases (Table 1).

This study uncovers a unique broad neutralization mechanism against rotavirus, where antibody 7H13 destabilizes the partial structure of the viral VP4 spike by acting on a critical residue switch ...