Breast cancer (BC) is one of the most common malignancies and the leading cause of cancer-related mortality in women. Androgen receptor (AR) is frequently expressed in diverse BC subtypes.

The team has reported that androgen receptors are as important for sexual development and fertility in females as in males. Specifically, the researchers found that both male and female chickens ...

It was not until later that it was discovered that androgen insensitivity was caused by mutations in the androgen receptor gene. The symptoms of androgen insensitivity depend on the type. Individuals ...

1Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. 2Department of Radiation Oncology, University of California, San Francisco, San ...

1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

These included genetic models such as androgen receptor knockout mice and chronic androgen exposure in females using dihydrotestosterone (DHT) implants. Subsequently, they analyzed DNA from ...

and it also blocks androgen receptors in the skin. Estrogen stimulates angiotensin synthesis and enhances aldosterone-mediated water and sodium retention, making it responsible for such unpleasant ...

Adrenal insufficiency or bilateral oophorectomy (surgical menopause) result in severe androgen deficiency, which can be clinically associated with impaired libido, drive and energy. Physiological ...

A popular biological psychological explanation is the "Extreme Male Brain Theory" (EMB), which suggests that an overdose of prenatal androgen (male hormone) leads to the hyper-masculine brain type ...