A man who should have developed early-onset Alzheimer's disease due to a genetic mutation is still symptom-free in his 70s.

A recent study published in eLife offers a new perspective on the development of Alzheimer’s disease, suggesting that the ...

During her talk, Rice had described how a peptide called amyloid precursor protein (APP) gets broken down in the brain into smaller pieces such as amyloid-β, the peptide that notoriously goes on to ...

Increasing focus is now being placed on the production of Aβ – a process called proteolysis, during which a precursor protein called amyloid precursor protein (APP) is trimmed by an enzyme ...

Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,” Charles Piller looks how the amyloid hypothesis took over ...

Two main protein structures are associated with Alzheimer’s disease: amyloid-beta plaques and neurofibrillary tangles (NFTs).

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to ...

In addition to the formation of senile plaques and neurofibrillary tangles in brain, the pathological hallmarks of Alzheimer disease (AD), there is substantial neuronal and synaptic loss in the ...

There exists no ‘amyloid cabal’” in Alzheimer’s research, neurologist Dennis Selkoe writes in response to Charles Piller’s ...

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always ...

Progress in deciphering the fundamental biological mechanism of Alzheimer's disease (AD) is proceeding at an impressive pace. A consensus has emerged among many investigators that cerebral ...

Two main protein structures are associated with Alzheimer’s disease: amyloid-beta plaques and neurofibrillary tangles (NFTs). Amyloid-beta: As Alzheimer’s disease develops, amyloid precursor ...