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Menin:维持肺癌细胞内稳态的关键 “管家”
研究发现,MEN1-KD 抑制了自噬体的形成,且这种调节方式不依赖于 mTORC1 和 AMPK 通路。通过对 TCGA-LUAD 和 A549 细胞的转录 ... 此外,Menin 对溶酶体和线粒体基因的调节不依赖于 P53-RB1 通路。 研究结论和讨论部分指出,Menin 是一种新型的转录调节因子,通过表观遗传 ...
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