When miRNA acts as the guide for RNAi, only a short part of the molecule ... This often results in a 100 percent match between guide and target, with very low off-target activity. Additionally, siRNAs ...

It might seem strange that miRNA-loaded Argonaute proteins can ... tethering functional human Argonautes to the target RNA can induce gene silencing 77. These data indicate that the small RNA ...

As gene expression profiling reaches a plateau and begins to face limitations, miRNA signature is a rising star that may provide new resolutions to old problems. It is difficult to say whether ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

RNAi is widely used to study gene function by selectively silencing specific genes and observing the resulting phenotypes ... and genetic disorders. By designing siRNAs or miRNA mimics that target ...

Now, researchers from SLU and the James Hutton Institute have for the first time investigated how spray-induced gene silencing affects other microorganisms. Fusarium head blight is a major disease ...