Our ultimate goal is to define if manipulating the cytoskeleton of cancer cells will lead to improved efficacy of therapeutic approaches in patients with metastatic disease, with a special focus on ...

Our laboratory is focusing on identification of metastasis and tumor cell invasion-associated molecules, by using advanced molecular biology and the phage display technology. We are also developing ...

Current statistics for breast cancer show that survival could be significantly increased with better and earlier diagnosis of patients who are at risk of malignant progression. Cellular mechanisms ...

Research projects in the tumor invasion and metastasis theme of the Department of Cancer Biology aim to expand translational research on the processes that enable tumor cells to invade surrounding ...

The anterior gradient-2 (AGR2) can be secreted to extracellular compartments and contribute to colorectal cancer (CRC) metastasis. We investigated the cellular source for secreted AGR2 in the TME and ...

An enzyme called MICAL2 promotes tumor growth and metastasis in the most common form of pancreatic cancer, according to a new study. Pancreatic cancer kills 50,000 people each year, according to ...

Cancer metastasis -- the spread of cancer to other organs -- is the leading cause of death among cancer patients. Researchers have now uncovered a 'genetic signature' of 177 genes shared across ...

Back to Finland she founded her own research group of Translational Cancer Biology in the Research Program Unit of the Faculty of Medicine, University of Helsinki, Finland. She currently leads key ...

Metastasis causes >90% of cancer death. The emergence, persistence, therapy resistance and lethality of metastatic cancer is driven by dynamic and tenacious metastasis stem cells (MetScs). The Ganesh ...