Coya Therapeutics, Inc. (NASDAQ:COYA) announced the expansion of its investigational pipeline and advancement of COYA 303 for ...

As they continue their work, Ferreira and his team are continuing to investigate how a CAR affects a Treg's work. "We're trying to understand the mechanism of the intrinsic signaling [changes ...

This challenge has focused researchers on understanding Tregs' tumor-specific mechanisms to selectively target Tregs within ...

Gene regulation in immune cells refers to the mechanisms used by immune cells ... central tolerance via clonal deletion and regulatory T cell induction. Here the authors show, using mouse bone ...

Major areas of interest include: the molecular and cellular mechanisms governing the differentiation and function of regulatory T cells; the roles these cells play in control of autoimmunity, tumor ...

This reduces T-cell activation and cytokine production, as well as encouraging Treg cell recruitment to the fetal–maternal interface. These changes are critical in promoting maternal tolerance.