Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...
调节性T细胞是维持机体免疫稳态的CD4+ T细胞亚群,也是肿瘤微环境中免疫抑制屏障的主要构成细胞。因此,特异性地调控肿瘤微环境的Treg细胞使其功能与稳定性发生改变,将能够促进肿瘤杀伤反应的发生。
在一项新的研究中,来自南卡罗来纳医科大学霍林斯癌症中心的研究人员揭示了如何设计嵌合抗原受体(chimeric antigen receptor, CAR)Treg细胞的新规则。这一突破可能为对抗1型糖尿病等自身免疫性疾病提供更有效的工具。
There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function ...
Researchers at the University of Adelaide's Robinson Research Institute have uncovered a new critical role for the immune ...
Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...
A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after ...
A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research ...
Tumor tissue and ascites from patients with ovarian cancer contain high levels of cells with all the hallmarks of regulatory T cells. These cells migrate into the tumor microenvironment in a ...