The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

cell communication and transcriptional regulation, consistent with the expected role of Foxp3 in Treg differentiation. Thus, the role of Foxp3 as a forkhead nuclear transcription factor regulating ...

Major areas of interest include: the molecular and cellular mechanisms governing the differentiation and function of regulatory T cells; the roles these cells play in control of autoimmunity, tumor ...

VD inhibits of Th1 cell differentiation and the production of Th1-specific cytokines. VD facilitates Treg cell generation and activity. VD has a role in the prevention of autoimmune diseases such ...

The alliance is focusing initially on two disease areas – type 1 diabetes and inflammatory bowel disease – and revolves around Quell’s T-regulatory (Treg) cell platform, an area of ...

Research reveals how the dietary flavonoid promotes regulatory T cell development and suppresses ... the master transcription factor for Treg differentiation. Read the full story here.