The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...
VD facilitates Treg cell generation and activity. VD has a role in the prevention of autoimmune diseases such as multiple sclerosis, Type 1 diabetes, Crohn's diseases, ulcerative colitis and ...
Furthermore, they discovered that PRDM1-S was overexpressed in various autoimmune diseases, indicating that this could be a common characteristic of regulatory T-cell dysfunction.