Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

The body’s defense system against infection also fights tumors, generating tumor resident stem ... naive CD8+ T cells present in lymph nodes. The stimulated T cells can then migrate to the tumor. In ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

Human induced pluripotent stem (hiPS) cells refer to stem cells derived from adult somatic cells like blood or skin cells ... and elucidated the role of CD8 + T cells in regulating the immune ...

Researchers have discovered that some CAR-T cells ... cells specifically could be boosted by targeting genes like RUNX2. The cells also lived longer and reproduced more quickly than memory cells.

They found that naïve cells specifically could be boosted by targeting genes like RUNX2. The cells also lived longer and reproduced more quickly than memory ... states of CD8+ CAR T cells during ...