These issues are largely resolved by using iPS stems cells that arise from somatic cells because they can be recovered from an adult source. Furthermore, if cells are recovered from a human donor ...

Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells that can remain unrepaired for years. While most types of DNA damage are ...

We provide locally derived human pluripotent stem cell lines and generate induced pluripotent stem cell (iPSC) lines from somatic cells provided by the client. BSCC operates on a fee-for-service basis ...

This segregates the DNA most recently replicated, and therefore most error-prone, into cells destined for differentiation – which, in highly renewable tissues, are soon shed. (SSC indicates somatic ...

Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and ...

Throughout our life, all of the cells in our body accumulate genetic errors in the genome, known as somatic mutations. These can be caused by damaging environmental exposures, such as smoking ...

A new research paper titled "Disruption of mitochondrial unfolded protein response results in telomere shortening in mouse oocytes and somatic cells" has been published in Aging. Caseinolytic ...