These issues are largely resolved by using iPS stems cells that arise from somatic cells because they can be recovered from an adult source. Furthermore, if cells are recovered from a human donor ...

Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...

The pair had helped identify a still-unnamed disease, which they had tied to a particular gene and to a particular somatic mutation—a genetic change that had not been passed down from a parent and was ...

New research shows persistent DNA lesions in stem cells contribute to mutations, with links to blood cancers and external ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

A team of stem cell scientists successfully spawned mice from two male parents that reached adulthood, a significant step, ...

Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and ...

Throughout our life, all of the cells in our body accumulate genetic errors in the genome, known as somatic mutations. These can be caused by damaging environmental exposures, such as smoking, as well ...