随着生物技术的不断进步,细胞生物学正朝着更细致和系统化的方向发展。Hyman博士的研究为行业揭示了生物体内复杂结构的运作机制,并提出了结合新技术进行细胞组织研究的重要性。这不仅为基本生物学的研究提供了新的视角,也可能在生物医学工程、细胞治疗等领域带来 ...
Figure 2: A model for RNAi/PTGS/quelling. Several laboratories that study C. elegans have initiated genome-wide screens, based on an RNAi approach, to identify genes essential for completion of ...
中心体是微管组织中心,在细胞分裂中发挥着关键作用。中心体RNA(cnRNAs)在多个物种中已被发现存在,并被证实在许多物种的细胞分裂过程中精确调控基因表达的时空动态。然而,目前尚不清楚秀丽隐杆线虫(C.
Figure 3: Roles of the Argonaute complex in miRNA and RNAi pathways. Seminal studies in C. elegans and plants have uncovered the important role carried out by Argonaute proteins in RNA silencing ...
RNAi in Plants I take exception with your claim in The Scientist1 that RNAi was first discovered in Caenorhabditis elegans. While the term "RNAi" was first coined by Fire and colleagues,2 several ...
The roundworm C. elegans is a simple animal whose nervous system has exactly 302 neurons. Each of the connections between ...
Mackie and colleagues present a valuable comparison of lateralized gustation in two well-studied nematodes. The evidence they present that ASEL/R lateralization exists and is achieved by different ...
Using $1.8 million in federal funding, a biologist at The University of Texas at Arlington is heading up a project that could ...
More information: A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance, PLoS Genetics (2024). DOI: 10.1371/journal.pgen.
Areas of expertise Our research group is taking advantage of the genetic tractability and the availability of the entire genome sequence of C. elegans to gain an integrated understanding of organismal ...