Figure 2: A model for RNAi/PTGS/quelling. Several laboratories that study C. elegans have initiated genome-wide screens, based on an RNAi approach, to identify genes essential for completion of ...
Figure 3: Roles of the Argonaute complex in miRNA and RNAi pathways. Seminal studies in C. elegans and plants have uncovered the important role carried out by Argonaute proteins in RNA silencing ...
RNAi in Plants I take exception with your claim in The Scientist1 that RNAi was first discovered in Caenorhabditis elegans. While the term "RNAi" was first coined by Fire and colleagues,2 several ...
Mackie and colleagues present a valuable comparison of lateralized gustation in two well-studied nematodes. The evidence they present that ASEL/R lateralization exists and is achieved by different ...
More information: A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance, PLoS Genetics (2024). DOI: 10.1371/journal.pgen.
Areas of expertise Our research group is taking advantage of the genetic tractability and the availability of the entire genome sequence of C. elegans to gain an integrated understanding of organismal ...