RNA sequence design is a crucial area of research that focuses on creating RNA sequences that can fold into specific desired structures. This process is essential for various applications ...
Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...
When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...
No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...
Both the sequence of bases and the three-dimensional structure of RNA are determining factors in the great versatility of functions that characterize the molecule. The team used the mechanical ...
The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...